Sjogrens Syndrome and Sicca Symptoms in Patients with Systemic Sclerosis

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Sjögren’s Syndrome and Sicca Symptoms in Patients with Systemic Sclerosis

Introduction: Several autoimmune diseases can be accompanied by dysfunction of the salivary glands, regardless of the presence or absence of association with Sjögren’s syndrome (SS). A recent study by Maeshima et al. found salivary hyposecretion in 58.3% of patients with various connective tissue diseases, particularly systemic sclerosis (SSc). Objective: To determine the prevalence of SS and s...

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Treatment of sicca symptoms with hydroxychloroquine in patients with Sjogren's syndrome.

OBJECTIVE There is no established disease-modifying treatment of xerostomia and xerophthalmia in SS. This retrospective study was performed in order to evaluate the efficacy of HCQ for glandular function, i.e. saliva and tear production. METHODS Fourteen patients with primary SS (pSS) were included (Group A). All patients were anti-Ro and/or -La antibody positive except one. Patients were tre...

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Sicca symptoms and secondary Sjögren's syndrome in systemic lupus erythematosus: comparison with rheumatoid arthritis and correlation with disease variables.

OBJECTIVE Firstly, to study the prevalence of ocular and oral sicca symptoms, reduced tear and saliva production, and the minimum frequency of secondary Sjögren's syndrome (sSS) in systemic lupus erythematosus (SLE). Secondly, to compare sicca symptoms and findings with those of matched patients with rheumatoid arthritis (RA), and sicca symptoms with those in healthy controls. Finally, to study...

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Diagnostic tests in patients with symptoms of keratoconjunctivitis sicca.

We compared the relative value of the tear film breakup time, Schirmer test, lactoferrin immunologic assay and rose bengal staining in 156 patients with varying severity of symptoms characteristic of keratoconjunctivitis sicca and in 39 controls. Statistical analysis showed that in patients with minimal ocular irritation the Schirmer test in combination with the lactoferrin immunologic assay pr...

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ژورنال

عنوان ژورنال: Journal of Arthritis

سال: 2015

ISSN: 2167-7921

DOI: 10.4172/2167-7921.1000190